Dentin chondrogenic inductive agent
US4935497A · kind A · utility
6Cited by
3References
2Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 6, 1988 |
| Grant date | Jun 19, 1990 |
| Priority date | — |
| Expiry date | Sep 6, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A cartilage-inducing factor has been isolated from dentin and characterized as a polypeptide having an apparent molecular weight of 6,000 to 8,500, an isoelectric pH of from 4.5 to 6.5, and, biologically, as being capable of inducing muscle fibroblast cells to produce cartilage-specific proteoglycan and Type II collagen.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.