Apparatus and method for determining functions of cells
US4936674A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 7, 1989 |
| Grant date | Jun 26, 1990 |
| Priority date | — |
| Expiry date | Apr 7, 2009 |
Classification
- Technology area (CPC G)Physics
- CPC primaryG01N2015/018
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
An apparatus for determining the functioning properties of cells which includes a sample containing chamber, a rotor disposed in the chamber and having a conical surface which faces the inner bottom surface of the chamber at an angle of not greater than 2.degree., a ray transmission path from which a ray is projected into a sample of a cell suspension between the rotor and the inner bottom surface, and a transmitted ray detection path from which transmittance from the sample is detected. The optical path length in the sample is not smaller than 1 cm. An adequate shear stress is applied to the sample by adjusting the gap between the rotor and the inner bottom surface and rotating the rotor. A fine response by the cells caused by the applied shear stress, particularly the aggregation of platelets in a platelet suspension, can be accurately and quantitatively determined with a high sensitivity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.