Method for the preparation of antibody-fragment conjugates
US4937183A · kind A · utility
46Cited by
3References
24Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Feb 3, 1988 |
| Grant date | Jun 26, 1990 |
| Priority date | — |
| Expiry date | Feb 3, 2008 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/866
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel method for preparing soluble antibody fragment compositions having superior characteristics for targeted delivery when administered in vivo are disclosed. The antibody fragment compositions are characterized by substantially the same immunospecificity as the unconjugated antibody and aqueous solubility such that they are suitable for in vivo administration. Therapeutic and diagnostic methods utilizing the antibody fragment compositions are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.