Translation enhancer
US4937190A · kind A · utility
76Cited by
0References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Oct 15, 1987 |
| Grant date | Jun 26, 1990 |
| Priority date | — |
| Expiry date | Oct 15, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N15/67
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Disclosed in this patent are DNA sequences, RNA sequences, vectors, and hosts that incorporate a translation enhancer region derived from the 5' non-coding region of a cardiovirus. The enhancer acts at the RNA level (as opposed to the DNA level) to enhance production of proteins in cell free media. Proteinaceous material which is produced will not have attached to it any undesired material from the enhancer sequence. The invention is especially useful to enable efficient production of selected viral proteins of picornoviruses.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.