1-acyl indazoles
US4937247A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Sep 25, 1987 |
| Grant date | Jun 26, 1990 |
| Priority date | — |
| Expiry date | Sep 25, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D453/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of formula (I) and pharmaceutically acceptable salts thereof: ##STR1## wherein X is CH or N; PA0 Y is NH or O; PA0 R.sub.1 is hydrogen or halogen; PA0 R.sub.2 is a group of formula (a), (b) or (c) ##STR2## wherein n is 2 or 3; p and q are independently 1 to 3; and R.sub.4 or R.sub.5 is C.sub.1-4 alkyl; PA0 R.sub.3 i s C.sub.1-10 acyl, C.sub.1-6 alkoxycarbonyl, optionally substituted phenoxycarbonyl or benzyloxycarbonyl, or R.sub.6 R.sub.7 NCO or R.sub.6 R.sub.7 NS(O).sub.m wherein m is 1 or 2 and R.sub.6 and R.sub.7 are independently C.sub.1-6 alkyl groups or together are C.sub.4-6 polymethylene; having 5-HT.sub.3 antagonist activity, a process for their preparation and their use as pharmaceuticals.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.