Water insoluble derivatives of hyaluronic acid
US4937270A · kind A · utility
129Cited by
2References
42Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 18, 1987 |
| Grant date | Jun 26, 1990 |
| Priority date | — |
| Expiry date | Sep 18, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61L31/145
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method for making a water insouble bicompatible gel includes activating HA with an activating agent to form activated HA, and reacting the activated HA with a nucleophile, under conditions producing the water insoluble bicompatible gel. Also, a method for making a water insoluble biocompatible film includes providing a biocompatible gel made according to the above method, and drying the gel or compressing the gel under conditions permitting escape of water from the gel. Also, a water insoluble composition including HA is prepared without the use of any bifunctional or polyfunctional nucleophile.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.