Phenyl-azacykloalkanes

US4937346A · kind A · utility

Assignee

• Per A. E. Carlsson · SE

Inventors

• Folke L. Arvidsson · Uppsala, SE
• Per A. E. Carlsson · Göteborg, SE
• Uli A. Hacksell · Uppsala, SE
• John S. M. Hjorth · Göteborg, SE
• Per L. Lindberg · Mölndal, SE
• John L. G. Nilsson · Tullinge, SE
• Domingo Sanchez · Floda, SE
• Nils U. E. Svensson · Brunna, SE
• Hakan V. Wikstrom · Mölndal, SE

Key dates

• Filing date: Nov 30, 1987
• Grant date: Jun 26, 1990
• Expiry date: Nov 30, 2007

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D213/30
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compound of the formula ##STR1## wherein n is 1 or 2, Y is OH, R.sup.1 COO--, R.sup.2 R.sup.3 NCOO-- or R.sup.4 O whereby R.sup.1 is an alkyl group, or a possibly substituted phenyl group, R.sup.2 is an alkyl, phenethyl, or benzyl or phenyl group, R.sup.3 is H or an alkyl group and R.sup.4 is an allyl or benzyl group, and R is an alkyl, hydroxyalkyl, dimethylaminoalkyl or methylthioalkyl group or alkenyl group, processes for their preparations and methods of treatment employing such compounds. The compounds are useful for therapeutic purposes, especially for treatment of disorders in the central nervous system.