Pharmaceutical formulations
US4938967A · kind A · utility
45Cited by
2References
21Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 17, 1987 |
| Grant date | Jul 3, 1990 |
| Priority date | — |
| Expiry date | Sep 17, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/1611
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The residence time in the human stomach of pharmaceutical, gastric controlled release, solid units can be increased significantly if the units have a density that is much higher than normal. A preferred oral dosage form according to the invention comprises a capsule or other dosage form having a dimension above 2 mm and that contains one or more of the said units. The density of each unit is preferably at least 2.5 and usually at least 2.7 g/ml and can conveniently be achieved by including at least 50% by weight of a weighting agent such as barium sulphate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.