Sustained production of recombinant gamma interferon using an Epstein-Barr virus replicon
US4939088A · kind A · utility
7Cited by
1References
20Claims
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Key dates
| Filing date | Feb 18, 1987 |
| Grant date | Jul 3, 1990 |
| Priority date | — |
| Expiry date | Feb 18, 2007 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2710/16243
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A recombinant DNA expression vector comprising an Epstein-Barr virus origin of replication, an EBNA-1 gene, a selectable marker expression cassette and a human gamma interferon expression cassette comprising a promoter region, an open reading frame encoding human gamma interferon and a polyadenylation region; a mammalian host cell transformed by said vector; and a process for producing human gamma interferon using said transformed mammalian host cell.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.