Patent · US Expired

1-pyrrolidineacetamide derivatives and use thereof

US4939126A · kind A · utility

9Cited by
3References
10Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 11, 1988
Grant dateJul 3, 1990
Priority date
Expiry dateJul 11, 2008

Classification

  • Technology area (CPC A)Human Necessities
  • CPC primaryA61P25/28
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

1-Pyrrolidineacetamide derivatives of the formula ##STR1## wherein R.sub.1 is hydrogen atom or a trialkylsilyl group, R.sub.2 and R.sub.3 are hydrogen atom, respectively, when R.sub.1 is hydrogen atom, R.sub.4 is an alkyl group, R.sub.5 is a radical of ##STR2## in which R.sub.6 and R.sub.7 are an alkyl group, respectively, m and n are an integer of 1 to 3, respectively, PA1 or R.sub.4 represents together with R.sub.5 a hetero cyclic ring having nitrogen and silicon atoms or piperazine ring having a substituent of ##STR3## in which R.sub.6 and n have the meanings as referred to, and R.sub.2 and R.sub.4 as well as R.sub.3 and R.sub.5 form a hetero cyclic ring, respectively, connected with an alkylene chain, where R.sub.1 is the trialkylsilyl group, salts thereof, a process for the preparation thereof, as well as use thereof as for a medicine.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.