Novel 5-alkylsulfonylsalicylanilides and microbiocidal compositions for controlling the growth of microorganisms
US4939132A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 15, 1985 |
| Grant date | Jul 3, 1990 |
| Priority date | — |
| Expiry date | Apr 15, 2005 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
This invention relates to new 5-alkylsulfonylsalicylanilides and methods for their use. More particularly, the invention relates to compounds of the formula: ##STR1## Wherein Z is a substituted or unsubstituted phenyl ring of from 6 to 30 carbon atoms including substituents, R is a substituted or unsubstituted alkylsulfonyl group of from 1 to 20 carbon atoms including substitutents; and X is a radical selected from the group consisting of --CN, --NO.sub.2, --H, halogen, lower alkyl or lower haloalkyl. The above compounds and compositions containing them are effective antiseptics against a wide range of microorganisms, especially bacteria, and are surprisingly highly effective against microorganisms, particularly S. mutans, prevalent in dental plaque.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.