Hexa-cyclic camptothecin derivatives
US4939255A · kind A · utility
26Cited by
5References
3Claims
0Family size
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Inventors
Key dates
| Filing date | Jun 16, 1988 |
| Grant date | Jul 3, 1990 |
| Priority date | — |
| Expiry date | Jun 16, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A novel hexa-cyclic compound, a derivative of camptothecin, of the general formula: ##STR1## The compound is prepared from an aminoketone compound and a pyranoindolizine compound through Friedlaender reaction. It has an excellent antitumor activity and a high degree of safety, and can be applied as an antitumor medicine for curing tumors of various kinds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.