Patent · US Expired

N-substituted derivatives of 1-desoxynojirimycin and 1-desoxymannonojirimycin and pharmaceutical use

US4940705A · kind A · utility

75Cited by

0References

9Claims

0Family size

Assignee

BAYER HEALTHCARE LLC · DE

Inventors

Horst Boshagen · Haan, DE
Bodo Junge · Wuppertal, DE
Arnold Paessens · Haan, DE
Matthias Schuller · Wuppertal, DE

Key dates

Filing date	Oct 26, 1988
Grant date	Jul 10, 1990
Priority date	—
Expiry date	Oct 26, 2008

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D453/02
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

N-substituted derivatives of 1-desoxynojirimycin and 1-desoxymannojirimycin of the formula ##STR1## in which one of R and R' are hydroxyl and the other is hydrogen PA0 n is a number from 1 to 6 PA0 R.sup.1 is hydrogen, alkyl or benzyl and PA0 R.sup.2 is alkyl which is optionally substituted by an optionally substituted aryl or by pyridyl, thienyl, furyl, pyrimidyl, pyrazinyl or quinolyl or R.sub.1 is cycloalkyl or R.sup.2 is optionally substituted by aryl or R.sup.2 is a saturated bridged heterocycle or R.sup.1 and R.sup.2 together can form a heterocyclic ring which is optionally substituted. These compounds are useful in the treatment of and prophylaxis of viral infections.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.