Patent · US Expired

Biosynthetic anthracyclines related to daunorubicin

US4942155A · kind A · utility

2Cited by
0References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 9, 1987
Grant dateJul 17, 1990
Priority date
Expiry dateMar 9, 2007

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC12R2001/465
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

##STR1## are prepared by a biosynthetic process based on the addition of sodium salt of 1,3-N,N-dimethylbarbituric acid and 2-thiobarbituric acid respectively during the fermentation process of different micro-organisms such as Streptomyces peucetius and its mutants. The novel compounds are provided with good antibacterial and antitumour activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.