Tetra- and pentapeptides containing the lysyl-arginyl-aspartyl sequence and their applications as medicines, particularly anti-thrombotic medicines
US4943562A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Oct 28, 1988 |
| Grant date | Jul 24, 1990 |
| Priority date | — |
| Expiry date | Oct 28, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P7/02
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
The peptides according to the invention are of the following general formula I: EQU Z-Lys-Arg-Asp-X-Y (I) wherein: PA1 X is the residue of one of the 20 common aminoacids in the L-configuration, PA1 Y is hydroxyl or the C-terminal residue of one of the 20 common aminoacids in the L-configuration, PA1 Z is acetyl, hydrogen or the N-terminal residue of one of the 20 common aminoacids in the L-configuration, as the case may be N-acetylated, whereby it is understood that: PA1 when Y is the C-terminal residue of one of the 20 common aminoacids in the L-configuration, Z is acetyl or hydrogen and PA1 X can in all cases be different from Y and from Z. Application to the preparation of anti-thrombotic medicines.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.