Antidiabetic phosphonates
US4945158A · kind A · utility
6Cited by
1References
17Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 12, 1988 |
| Grant date | Jul 31, 1990 |
| Priority date | — |
| Expiry date | Aug 12, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F9/65515
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Phosphonates are disclosed which stimulate the enzyme fructose-1,6-bisphosphatase and inhibit the enzyme 6-phosphofructo-1-kinase, thereby lowering glucose levels in mammals. These phosphonates may thus be used to treat hyperglycemia and/or diabetes. Processes for the synthesis of the phosphonates are also disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.