Anti-tumor DC-52 derivatives
US4946957A · kind A · utility
3Cited by
1References
1Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 30, 1989 |
| Grant date | Aug 7, 1990 |
| Priority date | — |
| Expiry date | Aug 30, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D498/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to novel derivatives of DC-52 represented by the following formula (I): ##STR1## [wherein X is chlorine, bromine, iodine, hydroxyl, formyl, hydroxyiminomethyl, cyano, nitro, amino or lower alkanoylamino; and Y is hydroxyl and Z is cyano, or Y and Z represent --O-- in the form of --Y--Z--]. These compounds and pharmacologically acceptable salts thereof have high anti-tumor activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.