Granular composition for ruminant
US4948589A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jan 5, 1989 |
| Grant date | Aug 14, 1990 |
| Priority date | — |
| Expiry date | Jan 5, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA23K40/35
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A granular composition for a ruminant containing as a main component choline or a physiologically acceptable derivative thereof, wherein the composition is prepared by (1) granulating the choline or it derivative having an average particle size of 100 .mu.m or less and a maximum particle size of 150 .mu.m or less, an excipient having an average particle size of 10 .mu.m or less and a maximum particle size of 20 .mu.m or less, and a hydrophobic binder under a relative humidity of 10% or less by using an agitation granulator, followed by cooling, separating and classifying the resultant granules to obtain spherical granules having a particle size of 0.5 to 2.5 mm and (ii) forming a thin film on the surface of the granules at a temperature of at least 5.degree. C. less than a melting point of the binder and 5.degree. C. to 25.degree. C. less than a melting point of the overcoating agent under a relative humidity of 30% or less in an agitation granulator by adding 20 to 40 parts by weight, based on 100 parts by weight of the granules, of a heated molten mixture of a hydrophobic overcoating agent and a solubility modifier in the form of a fine powder in a weight ratio of 1:0.2-1.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.