Method for the preparation of coated solid medicament form
US4948622A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 9, 1988 |
| Grant date | Aug 14, 1990 |
| Priority date | — |
| Expiry date | Jun 9, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K9/5073
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Solid medicament forms, such as granules, beads, tablets, are first coated with a hot aqueous dispersion of a cellulose ether, which is soluble in cold water but insoluble in hot water, and then subjected to a wax treatment with heating to form a masking layer of the wax. Different from the coating film of a cellulose ether formed by using an aqueous or organic solution of the cellulose ether, the coating film formed by using the aqueous dispersion of the cellulose ether has a porous structure so that the amount of the wax deposited in the wax treatment is much larger than in the prior art methods to exhibit a high effect of masking the bitterness of the ingredient contained in the medicament form.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.