Chemical sensor
US4948727A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Oct 11, 1985 |
| Grant date | Aug 14, 1990 |
| Priority date | — |
| Expiry date | Oct 11, 2005 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/817
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
The present invention is concerned with a chemical sensor, more specifically with a chemical sensor which is capable of detecting the presence of, measuring a quantity of or monitoring the level of N-acetyl primary aromatic amines, such as paracetamol, in whole blood. The specification relates to a method of assay of the type in which an electrode poised at a suitable potential is contacted with a system comprising; PA1 (a) a sample suspected to contain paracetamol or a derivative thereof, and PA1 (b) an enzyme capable of catalyzing the hydrolysis of an N-acylated primary aromatic amine or a derivative thereof, and, wherein the current flowing in the electrode is a measure of the quantity of hydrolysis products formed and thereby of the concentration of N-acylated primary aromatic amine or derivatives thereof in the sample.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.