Guanidine carboxylic acid esters and pharmaceutical preparations containing these compounds

US4948802A · kind A · utility

Assignee

• Heumann Pharma GmbH · DE

Inventors

• Peter Morsdorf · Langenzenn, DE
• Helmut Schickaneder · Eckental, DE
• Volker Pfahlert · Munich, DE
• Heidrun Engler · Cadolzburg, DE
• Armin Buschauer · Berlin, DE
• Walter Schunack · Berlin, DE

Key dates

• Filing date: Apr 11, 1988
• Grant date: Aug 14, 1990
• Expiry date: Apr 11, 2008

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

New guanidine carboxylic acid esters corresponding to the general formula I ##STR1## and a process for the preparation of these compounds are described. The compounds according to the invention are H.sub.2 -agonists optionally having an additional H.sub.1 -antagonistic component. They are distinguished by their improved oral activity. The use of the above-mentioned guanidine carboxylic acid esters and of pharmaceutical preparations containing these esters is also described.