Patent · US Expired

Renin inhibitors containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues

US4948913A · kind A · utility

1Cited by
3References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 2, 1987
Grant dateAug 14, 1990
Priority date
Expiry dateNov 2, 2007

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S530/86
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

A series of novel polypeptide derivatives, containing 5-amino-2,5-disubstituted-4-hydroxypentanoic acid residues, which are useful for inhibiting the angiotensinogen-cleaving action of the enzyme renin. Particularly valuable precursors for many of these compounds are certain other 5-amino-2,5-disubstituted-4-hydroxypentanoic acid derivatives.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.