Optically-active isomers of dideoxycarbocyclic nucleosides
US4950758A · kind A · utility
23Cited by
8References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 23, 1988 |
| Grant date | Aug 21, 1990 |
| Priority date | — |
| Expiry date | Dec 23, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D487/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Antiviral and antitumor compounds are disclosed of general formula: ##STR1## wherein Z is H, OR' or NH.sub.2, wherein R' is H, (C.sub.1 -C.sub.4)-alkyl, aryl, CHO, (C.sub.1 -C.sub.16)alkanoyl or O.dbd.P(OH).sub.2, Y is CH or N, and X is selected from the group consisting of H, N(R.sub.2), SR, OR' or halogen, wherein R is H, lower-(C.sub.1 -C.sub.4)alkyl, aryl or mixtures thereof, and the pharmaceutically-acceptable salts thereof.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.