Heat sealable membrane for transdermal drug release
US4951657A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 22, 1988 |
| Grant date | Aug 28, 1990 |
| Priority date | — |
| Expiry date | Apr 22, 2008 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G18/61
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A transdermal drug delivery system, is provided which includes, in combination, an impermeable backing member, a release rate controlling membrane, and, a reservoir containing a medicinally active ingredient; the improvement in such system is based on the fact that said membrane is heat and pressure sealed to said backing without the use of a separate adhesive and is formed of a substantially linear block copolymer which is a reaction product of an amino functional polydiorganosiloxane which forms soft segments in said reaction product and a diisocyanate which forms "hard" segments, said copolymer having a glass transition temperature between 50.degree. C. and 200.degree. C. said soft segments comprising from 60 to 90 percent by weight, based on the weight of said copolymer.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.