Drug-monoclonal antibody conjugates
US4952394A · kind A · utility
83Cited by
2References
6Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Nov 23, 1987 |
| Grant date | Aug 28, 1990 |
| Priority date | — |
| Expiry date | Nov 23, 2007 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
There is disclosed a drug-monoclonal antibody conjugate wherein the antibody is linked to a antitumor drug using disulfide benzyl carbamate or carbonate as the linker. Also disclosed is a method of delivering an active antitumor drug to the site of tumor cells in a mammal by administering the drug-monoclonal antibody conjugate.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.