Patent · US Expired

Process for the preparation of 2-nitro-3-aminopyridine, and the intermediates which are formed in the reaction

US4952697A · kind A · utility

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0References

8Claims

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Assignee

Hoechst GmbH · DE

Inventors

Siegfried Planker · Bocholt, DE
Klaus Warning · Eppstein, DE
Gunter H. Herbst, deceased · Kelkheim, DE
Ulrike M. Herbst · Kelkheim, DE
Bettina S. Herbst · Kelkheim, DE
Georg Schaeffer

Key dates

Filing date	Aug 25, 1988
Grant date	Aug 28, 1990
Priority date	—
Expiry date	Aug 25, 2008

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D213/76
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

2-Nitro-3-aminopyridine is prepared by PA0 (a) reacting 3-aminopyridine with phosgen COCl.sub.2 or urea H.sub.2 NCONH.sub.2 to give N,N'-di-(3-pyridyl)-urea, PA0 (b) nitrating and N,N'-di-(3-pyridyl)-urea with nitric acid or with a mixture of nitric acid and sulfuric acid to give N,N'-di-(2-nitor-3-pyridyl)-urea, and PA0 (c) hydrolyzing said N,N'-di-(2-nitro-3-pyridyl)-urea to give 2-nitro-3-amino-pyridine. N,N'-di-(3-pyridyl)-urea and N,N'-di-(2-nitro-3-pyridyl)-urea, which are formed in the course of the reaction as intermediates are new compounds. The end product of the process, 2-nitro-3-aminonpyridine, is an intermediate in various specialized fields.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.