Method of producing standardized povidone iodine preparations and such preparations
US4954351A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 22, 1988 |
| Grant date | Sep 4, 1990 |
| Priority date | — |
| Expiry date | Sep 22, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P31/04
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A pharmaceutical iodophor preparation having predictable microbicidal effectiveness and long duration of action comprising polyvinylpyrrolidone-iodine (PVPI), free iodine, a source of iodide ions and a source of iodate ions, the preparation having a ratio of available (titratable) iodine to iodide between 2:1 and 10:1, a pH between 5 and 6 and a free iodine concentration between 2 and 20 ppm, wherein the amount of iodate ion in the preparation is sufficient to maintain the free iodine concentration between 2 and 20 ppm for at least 12 months at 20.degree. C.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.