6-substituted penem esters as anti-inflammatory and anti-degenerative agents
US4954493A · kind A · utility
2Cited by
4References
3Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 14, 1988 |
| Grant date | Sep 4, 1990 |
| Priority date | — |
| Expiry date | Jun 14, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
6-substituted penem esters of formula (I): ##STR1## wherein R.sub.1 is halogen or a C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy, phenyl, phenoxy, benzyl, or sulphonyloxy group; R.sub.2 is a C.sub.1 -C.sub.4 alkyl, benzyl diphenylmethyl ##STR2## group where A is C.sub.1 -C.sub.4 is C.sub.1 -C.sub.4 alkyl, benzyl, p-nitrobenzyl or p-methoxybenzyl; and R.sub.3 is an organic radical, are elastase inhibitors and thereby useful antiinflammatory and antidegenerative agents.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.