Piperazine substituted 6-phenyldihydro-3(2H)-pyridazinones, and pharmaceutical preparations containing these

US4954501A · kind A · utility

Assignee

• Heumann Pharma GmbH · DE

Inventors

• Rolf Herter · Schwabach, DE
• Peter Morsdorf · Langenzenn, DE
• Volker Pfahlert · Munich, DE
• Heidrun Engler · Cadolzburg, DE
• Helmut Schickaneder · Eckental, DE
• Kurt H. Ahrens · Nürnberg, DE

Key dates

• Filing date: Sep 21, 1988
• Grant date: Sep 4, 1990
• Expiry date: Sep 21, 2008

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D417/12
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

New 6-phenyldihydro-3(2H)-pyridazinones corresponding to the following general formula ##STR1## are described. These compounds are readily prepared in a form suitable for oral administration and are distinguished by a high positive inotropic action and have only a slight effect on blood pressure and cardiac frequency. A process for their preparation and pharmaceutical preparations containing these compounds are also described.