Use of 2,5-anhydro-d-mannitol as a food intake modifier
US4954531A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 15, 1988 |
| Grant date | Sep 4, 1990 |
| Priority date | — |
| Expiry date | Aug 15, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/34
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A novel method for altering the food intake of a mammal is diclosed wherein 2,5-anhydro-D-mannito (2,5-AM) is administered to that mammal in an amount sufficient to alter its food intake. Preferably, normal feeding and fasting periods, and most preferably diurnal feeding and fasting periods, are identified. The mammal receives an intragastric, or intraperitoneal, or intravenous administration within two hours in advance of the onset of the feeding period to decrease food intake, or within two hours of the onset of the fasting period to increase intake. The subject mannitol is preferably administered in amounts of 50-800 mg/kg, although neither the low limit of sufficiency nor the upper limit of activity have yet to be identified.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.