Substituted thienoimidazole derivatives, a process for the preparation thereof, pharmaceutical compositions containing them, and the use thereof as inhibitors of gastric acid secretion, as gastroprotectives and as medicaments for intestinal inflammations

US4956366A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Hildegard Nimmesgern · Frankfurt am Main, DE
• Klaus Weidmann · Kronberg, DE
• Hans-Jochen Lang · Hofheim, DE
• Robert Rippel · Hofheim, DE
• Andreas Herling · Bad Camberg, DE

Key dates

• Filing date: Jul 13, 1988
• Grant date: Sep 11, 1990
• Expiry date: Jul 13, 2008

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P1/12
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Substituted thienoimidazole derivatives, a process for the preparation thereof, pharmaceutical compositions containing them, and the use thereof as inhibitors of gastric acid secretion, as gastroprotectives and as medicaments for intestinal inflammations The invention relates to compounds of the formula ##STR1## in which A represents ##STR2## T denotes --S--, --SO-- or --SO.sub.2 --, R.sup.1 to R.sup.10, X, Y and Z have the meanings indicated in the description, to a process for the preparation thereof, to pharmaceutical compositions containing them, and to the use thereof as inhibitors of gastric acid secretion, as gastroprotectives and as medicaments for intestinal inflammations.