Immunologically active synthetic peptides useful for preparing an antimalarial vaccine
US4956449A · kind A · utility
1Cited by
12References
18Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 28, 1988 |
| Grant date | Sep 11, 1990 |
| Priority date | — |
| Expiry date | Nov 28, 2008 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY02A50/30
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Synthetic peptides consisting of at least two consecutive repeating units of the sequence (Ala-Asn-Asn-Pro) are powerful immunogens in experimental animals. The antibodies which form recognize both said synthetic peptides and the immunodominant epitope of the circumsporozoitic peptide of Plasmodium falciparum. Said peptides, obtainable in pure form, are particularly useful for preparing antimalarial vaccines and diagnostic kits for the determination of malarial affections.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.