Assay for antigens by binding immune complexes to solid supports free of protein and non-ionic binders
US4959303A · kind A · utility
36Cited by
8References
79Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Dec 21, 1987 |
| Grant date | Sep 25, 1990 |
| Priority date | — |
| Expiry date | Dec 21, 2007 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/828
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Methods are disclosed for detecting an antigen in a biological sample. The methods involve providing in combination a solid support, which is substantially free of specific binding proteins, and a medium comprising an antigen from the sample and an antibody for the antigen. The combination is incubated under conditions sufficient for the antibody when bound to the antigen to bind to the support. The presence or amount of antibody on the support or in the medium is determined and is related to the presence of antigen in the sample. The methods have particular application to the detection of gram-negative bacteria.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.