Quinolonecarboxamide compounds, their preparation and use as antivirals.
US4959363A · kind A · utility
72Cited by
7References
12Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 23, 1989 |
| Grant date | Sep 25, 1990 |
| Priority date | — |
| Expiry date | Jun 23, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D417/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formula ##STR1## where R is hydrogen, hydroxy, amino or lwer-alkyl; R.sup.1 is lower-alkyl, lower-alkenyl, cycloalkyl, pyridinyl, phenyl or substituted phenyl; R.sup.2 is hydrogen, amino or hydroxy; R.sup.6 is hydrogen or fluoro; and R.sup.7 is phenyl, pyridinyl or selected other heterocycles, have antiviral acitivity against herpes virus. The compounds are prepared from the corresponding carboxylic acids or ester, or by a tin-coupling reaction on the corresponding 7-halo compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.