Patent · US Expired

Crystalline cephalosporin compounds

US4959469A · kind A · utility

2Cited by
1References
3Claims
0Family size

Assignee

Inventors

Key dates

Filing dateFeb 27, 1989
Grant dateSep 25, 1990
Priority date
Expiry dateFeb 27, 2009

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D501/38
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The present invention relates to stable cyrstalline (6R,7R)-7-[(Z)-2-(2-aminothiazol-4-yl)-2-(1-carboxy-1-methylethoxyimino)ac etamido]-3-(5,6-dihydroxy-2-methyl-2-isoindolinium)-3-cephem-4-carboxylate sulfate or its hydrate, a process for production of the compound and (6R,7R)-7-[(Z)-2-(2-aminothiazol-4-yl)-2-(1-carboxyl-1-methylethoxyimino)a cetamido]-3-(5,6-dihydroxy-2-methyl-2-isoindolinium)methyl-3-cephem-4-carbo xylate hydrochloride or its hydrate which is a starting material useful for the production of the desired compound of the present invention.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.