Patent · US Expired

Methods for recovery of tissue plasminogen activator

US4960702A · kind A · utility

38Cited by
4References
46Claims
0Family size

Assignee

Inventors

Key dates

Filing dateMar 11, 1988
Grant dateOct 2, 1990
Priority date
Expiry dateMar 11, 2008

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/815
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Methods for recovering t-PA from a liquid medium are disclosed. The methods comprise contacting a liquid medium with at least one substrate capable of effecting a separation of intact t-PA from degraded t-PA thereafter recovering the intact t-PA free from other unrelated protein. The present invention also provides compounds produced by this method, compounds comprising intact one-chain t-PA and pharmaceutical compositions containing them and methods for using such compositions.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.