Methods for recovery of tissue plasminogen activator
US4960702A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 11, 1988 |
| Grant date | Oct 2, 1990 |
| Priority date | — |
| Expiry date | Mar 11, 2008 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S435/815
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Methods for recovering t-PA from a liquid medium are disclosed. The methods comprise contacting a liquid medium with at least one substrate capable of effecting a separation of intact t-PA from degraded t-PA thereafter recovering the intact t-PA free from other unrelated protein. The present invention also provides compounds produced by this method, compounds comprising intact one-chain t-PA and pharmaceutical compositions containing them and methods for using such compositions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.