Patent · US Expired

Chiral two-phase system and method for resolution of racemic mixtures and separation of diastereomers

US4960762A · kind A · utility

15Cited by

0References

14Claims

0Family size

Inventors

Börje Sellergren · Schwerte, DE
Björn Ekberg · Malmö, SE
Per-Ake Albertsson · Lund, SE
Klaus Mosbach · Halmstad, SE

Key dates

Filing date	Feb 27, 1987
Grant date	Oct 2, 1990
Priority date	—
Expiry date	Feb 27, 2007

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07B57/00
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

A chiral two-phase system for resolution of racemic mixtures, or for separation of diastereomers, is disclosed. The system comprises two immiscible liquid phases and one or more enantioselectively binding chiral components, each of which is substantially in one of said phases. Also disclosed is a method for chiral resolution of racemic mixtures, or for separation of diastereomers. Use is here made of the fact that different enantiomers are partitioned differently between the phases in the above-mentioned two-phase system in that one of the enantiomers is selectively bound to one of the chiral components which is substantially in one of said phases.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.