Pyrrolophthalazines
US4960775A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Dec 2, 1988 |
| Grant date | Oct 2, 1990 |
| Priority date | — |
| Expiry date | Dec 2, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P43/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Therapeutically useful pyrrolo[2,1-a]phthalazine derivatives of the formula: ##STR1## wherein R.sup.1 and R.sup.2 represent cycloalkyl, optionally substituted alkyl, alkenyl, alkynyl, aryl or heteroaryl, X represents ethylene or vinylene, R.sup.3 represents a group of the formula: EQU --Y--CH.sub.2 --CH(OH)--CH.sub.2 --COOR.sup.5 wherein Y represents carbonyl or hydroxymethylene and R.sup.5 represents hydrogen or optionally substituted alkyl, or R.sup.3 represents a lactone ring and the symbols R.sup.4 represent hydrogen, halogen, optionally substituted alkyl, alkenyl, alkynyl, aryl or heteroaryl, or R.sup.6 O-- wherein R.sup.6 represents alkyl, aryl or arylalkyl and salts thereof, processes for their preparation and compositions containing them are described.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.