Use of benzimidazole derivatives as yield promoters

US4960783A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Gerhard Bonse · Neunburg vorm Wald, DE
• Werner Hallenbach · Nordhorn, DE
• Hans Lindel · Leverkusen, DE
• Friedrich Berschauer · Wuppertal, DE

Key dates

• Filing date: Dec 30, 1988
• Grant date: Oct 2, 1990
• Expiry date: Dec 30, 2008

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D235/26
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Method of promoting the yield and growth of animals which comprises administering to such animals a yield and growth promoting effective amount of a benzimidazole derivative of the formula ##STR1## in which R.sup.1 stands for hydrogen, hydroxyl, alkyl or halogenoalkyl, PA1 R.sup.2 stands for hydrogen, alkyl, halogen, CN or halogenalkyl, PA1 R.sup.3 stands for hydrogen, alkyl or acyl, PA1 R.sup.4 stands for hydrogen, alkyl or halogenoalkyl, PA1 R.sup.5 stands for alkyl or halogenoalkyl, PA1 R.sup.6 stands for alkyl or cycloalkyl, which is optionally substituted by halogen, cycloalkyl, OH, alkoxy, halogenoalkoxy or aryl, which can in turn be substituted by alkyl, halogen, CN or the radicals --COR.sup.7, --O--alkylene--COR.sup.7, --alkylene--R.sup.8 or --O-- alkylene--R.sup.8, PA1 R.sup.7 stands for hydroxyl, alkoxy or --NR.sup.9 R.sup.10, PA1 R.sup.8 stands for hydroxyl, alkoxy or --NR.sup.9 R.sup.10, PA1 R.sup.9 stands for hydrogen or alkyl and PA1 R.sup.10 stands for hydrogen or alkyl, or physiologically tolerated salts thereof. The active materials are new except for those in which PA1 R.sup.1 stands for hydrogen, PA1 R.sup.4 stands for hydrogen, PA1 R.sup.5 stands for methyl and …