Production of 3-hydroxypropionaldehyde from glycerol by Klebsiella pneumoniae
US4962027A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 7, 1986 |
| Grant date | Oct 9, 1990 |
| Priority date | — |
| Expiry date | Aug 7, 2006 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12R2001/22
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A method is disclosed for producing 3-hydroxypropionaldehyde (3-HPA) from glycerol by culturing the bacterium Klebsiella pneumoniae having the identifying characteristics of NRRL B-4011, under aerobic conditions, in an aqueous nutrient medium containing glycerol and a compound that causes 3-HPA to be accumulated by blocking the conversion of 3-HPA to trimethylene glycol. This process is particularly useful for the production, from renewable resources, of acrylic acid, an industrially important plymerizable monomer used in the manufacture of synthetic polymers and plastics and which is presently derived from fossil fuel sources.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.