Renin inhibitor peptide compounds, a process for the preparation thereof and pharmaceutical composition comprising the same
US4963530A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Mar 21, 1988 |
| Grant date | Oct 16, 1990 |
| Priority date | — |
| Expiry date | Mar 21, 2008 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/86
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A compound of the formula: ##STR1## wherein R.sup.1 is aryl optionally substituted with a substituent selected from the group consisting of halogen and halo(lower)alkyl; lower alkyl or cyclo(lower)alkyl; and PA1 R.sup.2 is hydrogen or lower alkyl, or PA1 R.sup.1 and R.sup.2 are taken together with the attached nitrogen atom to form a heterocyclic group optionally substituted with a substituent selected from the group consisting of lower alkyl and esterified carboxy, PA1 R.sup.3 is hydrogen or lower alkyl, and PA1 R.sup.4 is lower alkyl, and its pharmaceutically acceptable salt, a process for the preparation thereof and pharmaceutical composition comprising the same.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.