1,4-dihydropyridine derivatives
US4963560A · kind A · utility
2Cited by
0References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 12, 1989 |
| Grant date | Oct 16, 1990 |
| Priority date | — |
| Expiry date | Sep 12, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P37/08
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
The invention provides compounds of the formula ##STR1## and pharmaceutically acceptable salts thereof, wherein R is phenyl substituted by halo; PA0 R.sup.1 is C.sub.1 -C.sub.4 alkyl; PA0 is hydrogen, C.sub.5 -C.sub.7 cycloalkyl, benzyl or C.sub.1 -C.sub.4 alkyl, said C.sub.1 -C.sub.4 alkyl group being optionally substituted by cyano, trimethylsilyl or C.sub.1 -C.sub.3 alkoxy; and PA0 "Het" is ##STR2## wherein R.sup.3 is hydrogen or methyl. The compounds are useful in the treatment of allergic, inflammatory and hypersecretory conditions, and circulatory shock, stroke and thrombosis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.