Boron analogs of amino acid/peptide protease inhibitors
US4963655A · kind A · utility
70Cited by
2References
3Claims
0Family size
Assignee
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Key dates
| Filing date | May 27, 1988 |
| Grant date | Oct 16, 1990 |
| Priority date | — |
| Expiry date | May 27, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K38/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
A method of inhibiting protease activity, growth, and colony formation in mammalian tumor cells by boronic acid analogs of amino acids, dipeptides and tripeptides. A method of coupling a boronic acid analog of an amino acid to other N-protected amino acids or N-protected dipeptides and compositions formed from the coupled products.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.