Patent · US Expired

Peptide compounds having a nitrogenous polycyclic structure

US4965250A · kind A · utility

15Cited by
3References
14Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJan 25, 1988
Grant dateOct 23, 1990
Priority date
Expiry dateJan 25, 2008

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07K5/0815
  • WIPO fieldBiotechnology
  • WIPO sectorChemistry

Abstract

Tetrapeptide compounds of general formula: ##STR1## in which R denotes: PA1 a hydrogen atom, PA1 a straight- or branched-chain alkyl radical containing from 1 to 4 carbon atoms, PA1 an aryl radical such as phenyl or a heterocyclic aromatic radical such as thienyl, optionally substituted with a hydroxy, amino, mercapto, methylthio or lower alkyl group, PA1 a lower aralkyl radical such as benzyl, PA0 R' denotes a hydrogen atom or a straight- or branched-chain alkyl group containing from 1 to 4 carbon atoms, PA1 X denotes an oxygen atom or an NH group, PA1 Y denotes an oxygen or sulfur atom when X denotes an NH group, or Y denotes an NH group when X denotes an oxygen atom, PA1 t denotes 0 or 1, ##STR2## denotes a nitrogen-containing polycyclic structure, their enantiomers, epimers and diastereoisomers, as well as their addition salts with a pharmaceutically acceptable acid or base. Medicinal products.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.