Patent · US Expired

Purine derivatives

US4965270A · kind A · utility

22Cited by
3References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateNov 7, 1989
Grant dateOct 23, 1990
Priority date
Expiry dateNov 7, 2009

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D473/32
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of formula (I), and pharmaceutically acceptable salts thereof: ##STR1## wherein R.sub.1 is hydrogen or CH.sub.2 OH; PA1 R.sub.2 is hydrogen or, when R.sub.1 is hydrogen, hydroxy or CH.sub.2 OH; PA1 R.sub.3 is CH.sub.2 OH or, when R.sub.1 and R.sub.2 are both hydrogen, CH(OH)CH.sub.2 OH; PA1 R.sub.4 is hydrogen, hydroxy, amino or OR.sub.5 wherein PA1 R.sub.5 is C.sub.1-6 alkyl, phenyl or phenyl C.sub.1-2 alkyl either of which phenyl moieties may be substituted by one or two halo, C.sub.1-4 alkyl or C.sub.1-4 alkoxy groups; and in which any OH groups in R.sub.1, R.sub.2 and R.sub.3 may be in the form of O-acyl, phosphate, cyclic acetal or cyclic carbonate derivatives thereof; having antiviral activity.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.