DHP delayed release preparation

US4966772A · kind A · utility

Assignee

• BAYER HEALTHCARE LLC · DE

Inventors

• Andreas Ohm · Neuss, DE
• Helmut Luchtenberg · Niederkassel, DE
• Manfred Bucheler · Overath, DE
• Roland Rupp · Bensberg, DE
• Heinrich Feltkamp · Hennef (Sieg), DE

Key dates

• Filing date: Apr 12, 1989
• Grant date: Oct 30, 1990
• Expiry date: Apr 12, 2009

Classification

• Technology area (CPC A): Human Necessities
• CPC primary: A61P9/10
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A solid medicament preparation having long-lasting action containing a sparingly soluble dihydropyridine active compound of the Formula (I) ##STR1## the preparation having a core-coating construction, the core containing at least one of the above mentioned dihydropyridines in slow-release form, the inner-most coating situated around the core contains no active compound and only dissolves slowly and adjacent to the inner-most coating a rapid release initial dose of the active compound mixed with a polymer.