4-substituted 17.beta.-(cyclopropyloxy)androst-5-en-3.beta.-ol and related compounds useful as C17-20 lyase inhibitors
US4966897A · kind A · utility
25Cited by
2References
8Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Aug 15, 1989 |
| Grant date | Oct 30, 1990 |
| Priority date | — |
| Expiry date | Aug 15, 2009 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07J1/0037
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention is directed to 4-substituted 17.beta.-(cyclopropyloxy)androst-5-en-3.beta.-ols and related compounds and also to a method for using such compounds in the treatment of androgen-dependent disorders. The ethers are prepared by using the Simmons-Smith reaction and an appropriate vinyl ether.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.