Radiohalogenated compounds for site specific labeling
US4966999A · kind A · utility
39Cited by
7References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 7, 1988 |
| Grant date | Oct 30, 1990 |
| Priority date | — |
| Expiry date | Jun 7, 2008 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Radiohalogenated compounds which are useful as intermediates for preparing radiohalogenated antibody conjugates in which the radiohalogenated compound is site specifically attached to an oxidized carbohydrate moiety of an antibody or antibody fragment are disclosed. Methods for making the compounds and the antibody conjugates as well as methods of use of the same are also disclosed In particular, phenolic hydrazide and phenolic amine compounds are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.