Use of purified hematoporphyrin trimers in photodynamic therapy
US4968715A · kind A · utility
87Cited by
1References
5Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Apr 26, 1989 |
| Grant date | Nov 6, 1990 |
| Priority date | — |
| Expiry date | Apr 26, 2009 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61P35/00
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Pure dimer and trimer compounds of hematoporphyrin are prepared and shown to be effective agents in photodynamic therapy. The compounds of the invention are of the formula ##STR1## wherein each X is independently 1-hydroxyethyl or vinyl and wherein R is H or lower alkyl. The compounds of the invention can be conjugated to targeting substances such as immunoglobulins or to labels.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.