Platinum complexes and antitumor agents containing them as an active ingredient
US4968826A · kind A · utility
6Cited by
2References
10Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Mar 16, 1990 |
| Grant date | Nov 6, 1990 |
| Priority date | — |
| Expiry date | Mar 16, 2010 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F15/0093
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel platinum complexes of the formula: ##STR1## wherein R.sup.1 and R.sup.2 each identically of differently is lower alkyl, or R.sup.1 and R.sup.2 taken together form --(CH.sub.2)m--, and m is an integer from 2 to 5, and antitumor agents comprising the compound (I), which are effective against cisplatin-resistant ascitic murine leukemia, murine leukemia, and solid tumor, with slight hemotoxicity and nephrotoxicity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.